HEMATOPOIESIS
We all know that when pathogens enter our body, they get absorbed in the
blood vessels. Our body has a well-connected network of blood vessels and
these blood vessels contain blood which contains cells and plasma. There are
about ten different types of cells in the blood vessels which can be classified
into three groups as shown in Red Blood Cells, White blood cells. T
and B Lymphocytes, natural killer cells, monocytes, neutrophils, eosinophils,
basophils) and platelets. White blood cells are the cells that protect our body
from pathogens.
Red blood cells, white blood cells, and platelets are produced in the bone
marrow and have a common precursor: a hematopoietic stem cell. Stem cells
have a characteristic ability to divide asymmetrically i.e., one daughter cell
continues to be a stem cell of the identical type, and at the same time, the
other daughter cell acquires a new identity. In the case of hematopoietic stem
cells, which are found in the bone marrow, one daughter cell remains a
hematopoietic stem cell, while the other goes on to become a different type of
stem cell: either a myeloid stem cell or a lymphoid stem cell.
The myeloid stem cells and lymphoid stem cells also divide asymmetrically,
with their non-stem cell daughters generating the mature cell types of the
blood. Myeloid stem cells give rise to red blood cells, platelets, and some
types of white blood cells, while lymphoid stem cells give rise to the types of
white blood cells classified as lymphocytes. Hematopoietic, myeloid,
and lymphoid stem cells divide throughout a person's lifetime, generating new
blood cells to replace old and worn-out ones.
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